Gene description for CD63
Gene name CD63 molecule
Gene symbol CD63
Other names/aliases AD1
HOP-26
ME491
MLA1
OMA81H
Pltgp40
TSPAN30
Species Homo sapiens
 Experiment description of studies that identified CD63 in Vascular smooth muscle cells

1
Experiment ID2012
Identified moleculeprotein
Extracellular vesicle typeLarge extracellular vesicles
MISEVLarge EVs
Identification method Western blotting
PubMed ID 36433666   
OrganismHomo sapiens
Experiment descriptionVascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization
AuthorsWhitehead M, Yusoff S, Ahmad S, Schmidt L, Mayr M, Madine J, Middleton D, Shanahan CM.
Journal name Aging Cell
Publication year2023
SampleVascular smooth muscle cells
Sample nameAorta-derived VSMCs
Isolation/purification methodsCentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

2
Experiment ID2013
Identified moleculeprotein
Extracellular vesicle typeMedium extracellular vesicles
MISEVLarge EVs
Identification method Western blotting
PubMed ID 36433666   
OrganismHomo sapiens
Experiment descriptionVascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization
AuthorsWhitehead M, Yusoff S, Ahmad S, Schmidt L, Mayr M, Madine J, Middleton D, Shanahan CM.
Journal name Aging Cell
Publication year2023
SampleVascular smooth muscle cells
Sample nameAorta-derived VSMCs
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

3
Experiment ID2014
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36433666   
OrganismHomo sapiens
Experiment descriptionVascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization
AuthorsWhitehead M, Yusoff S, Ahmad S, Schmidt L, Mayr M, Madine J, Middleton D, Shanahan CM.
Journal name Aging Cell
Publication year2023
SampleVascular smooth muscle cells
Sample nameAorta-derived VSMCs
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

4
Experiment ID2015
Identified moleculeprotein
Extracellular vesicle typeLarge extracellular vesicles
MISEVLarge EVs
Identification method Western blotting
PubMed ID 36433666   
OrganismHomo sapiens
Experiment descriptionVascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization
AuthorsWhitehead M, Yusoff S, Ahmad S, Schmidt L, Mayr M, Madine J, Middleton D, Shanahan CM.
Journal name Aging Cell
Publication year2023
SampleVascular smooth muscle cells
Sample nameAorta-derived VSMCs
Isolation/purification methodsCentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

5
Experiment ID2016
Identified moleculeprotein
Extracellular vesicle typeMedium extracellular vesicles
MISEVLarge EVs
Identification method Western blotting
PubMed ID 36433666   
OrganismHomo sapiens
Experiment descriptionVascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization
AuthorsWhitehead M, Yusoff S, Ahmad S, Schmidt L, Mayr M, Madine J, Middleton D, Shanahan CM.
Journal name Aging Cell
Publication year2023
SampleVascular smooth muscle cells
Sample nameAorta-derived VSMCs
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

6
Experiment ID2017
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36433666   
OrganismHomo sapiens
Experiment descriptionVascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization
AuthorsWhitehead M, Yusoff S, Ahmad S, Schmidt L, Mayr M, Madine J, Middleton D, Shanahan CM.
Journal name Aging Cell
Publication year2023
SampleVascular smooth muscle cells
Sample nameAorta-derived VSMCs
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

7
Experiment ID2018
Identified moleculeprotein
Extracellular vesicle typeLarge extracellular vesicles
MISEVLarge EVs
Identification method Western blotting
PubMed ID 36433666   
OrganismHomo sapiens
Experiment descriptionVascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization
AuthorsWhitehead M, Yusoff S, Ahmad S, Schmidt L, Mayr M, Madine J, Middleton D, Shanahan CM.
Journal name Aging Cell
Publication year2023
SampleVascular smooth muscle cells
Sample nameAorta-derived VSMCs - early passage
Isolation/purification methodsCentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

8
Experiment ID2019
Identified moleculeprotein
Extracellular vesicle typeMedium extracellular vesicles
MISEVLarge EVs
Identification method Western blotting
PubMed ID 36433666   
OrganismHomo sapiens
Experiment descriptionVascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization
AuthorsWhitehead M, Yusoff S, Ahmad S, Schmidt L, Mayr M, Madine J, Middleton D, Shanahan CM.
Journal name Aging Cell
Publication year2023
SampleVascular smooth muscle cells
Sample nameAorta-derived VSMCs - early passage
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

9
Experiment ID2020
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36433666   
OrganismHomo sapiens
Experiment descriptionVascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization
AuthorsWhitehead M, Yusoff S, Ahmad S, Schmidt L, Mayr M, Madine J, Middleton D, Shanahan CM.
Journal name Aging Cell
Publication year2023
SampleVascular smooth muscle cells
Sample nameAorta-derived VSMCs - early passage
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectometry
EV-TRACK -

10
Experiment ID2021
Identified moleculeprotein
Extracellular vesicle typeLarge extracellular vesicles
MISEVLarge EVs
Identification method Western blotting
PubMed ID 36433666   
OrganismHomo sapiens
Experiment descriptionVascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization
AuthorsWhitehead M, Yusoff S, Ahmad S, Schmidt L, Mayr M, Madine J, Middleton D, Shanahan CM.
Journal name Aging Cell
Publication year2023
SampleVascular smooth muscle cells
Sample nameAorta-derived VSMCs - late passage
Isolation/purification methodsCentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

11
Experiment ID2022
Identified moleculeprotein
Extracellular vesicle typeMedium extracellular vesicles
MISEVLarge EVs
Identification method Western blotting
PubMed ID 36433666   
OrganismHomo sapiens
Experiment descriptionVascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization
AuthorsWhitehead M, Yusoff S, Ahmad S, Schmidt L, Mayr M, Madine J, Middleton D, Shanahan CM.
Journal name Aging Cell
Publication year2023
SampleVascular smooth muscle cells
Sample nameAorta-derived VSMCs - late passage
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

12
Experiment ID2023
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36433666   
OrganismHomo sapiens
Experiment descriptionVascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization
AuthorsWhitehead M, Yusoff S, Ahmad S, Schmidt L, Mayr M, Madine J, Middleton D, Shanahan CM.
Journal name Aging Cell
Publication year2023
SampleVascular smooth muscle cells
Sample nameAorta-derived VSMCs - late passage
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectometry
EV-TRACK -

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